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Upregulation of MicroRNA-146a by Hepatitis B Virus X Protein Contributes to Hepatitis Development by Downregulating Complement Factor H
ABSTRACT Hepatic injuries in hepatitis B virus (HBV) patients are caused by immune responses of the host. In our previous study, microRNA-146a (miR-146a), an innate immunity-related miRNA, andExpand
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Directed shift of vaginal flora after topical application of sucrose gel in a phase III clinical trial: a novel treatment for bacterial vaginosis.
BACKGROUND Bacterial vaginosis (BV) is one of the most common infectious diseases among sexually active women and is associated with the increased acquisition of a variety of sexually transmittedExpand
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Tannin inhibits HIV-1 entry by targeting gp41.
AIM To investigate the mechanism by which tannin inhibits HIV-1 entry into target cells. METHODS The inhibitory activity of tannin on HIV-1 replication and entry was detected by p24 production andExpand
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Tactics used by HIV‐1 to evade host innate, adaptive, and intrinsic immunities
Objective To review the mechanisms by which HIV evades different components of the host immune system. Data sources This review is based on data obtained from published articles from 1991 to 2012. ToExpand
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[1,2,6-tri-O-galloyl-beta-D-glucopyranose inhibits gp41-mediated HIV envelope fusion with target cell membrane].
OBJECTIVE To observe the inhibitory effect of 1,2,6-Tri-O-galloyl-beta-D-glucopyranose (TGGP) from Balanophora japonica Makino on human immunodeficiency virus (HIV) entry into the host cells andExpand
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[Development of peptidic MERS-CoV entry inhibitors].
In 2012, a new SARS-like coronavirus emerged in the Middle East, namely the Middle East respiratory syndrome coronavirus (MERS-CoV). It has caused outbreaks with high mortality. During infection ofExpand
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[Rapid construction of a mammalian cell surface display library of full-length human antibodies].
OBJECTIVE To construct a mammalian cell surface display library of full-length human antibodies. METHODS The total RNA was isolated from human peripheral blood mononuclear cells (PBMCs), and theExpand
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[Construction of rheumatoid arthritis-specific full-length fully human mammalian display antibody libraries].
OBJECTIVE To construct a rheumatoid arthritis-specific full-length fully human mammalian display antibody libraries. METHODS Peripheral blood lymphocytes were isolated from patients with rheumatoidExpand
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[Study of the mechanism of caffeoyl glucopyranoses in inhibiting HIV-1 entry using pseudotyped virus system].
OBJECTIVE To investigate the inhibitory activities of caffeoyl glucopyranoses purified from Balanophora japonica Makino on HIV entry and their mechanism. METHODS HIV-1 Env pseudovirus was used toExpand
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[Effects of chemotherapy on the changes of histology and function of the ovary].