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Serum Levels of IL-6 and TNF-α May Correlate with Activity and Severity of Rheumatoid Arthritis
- Shi-Tong Wei, Y. Sun, Shi Zong, Y. Xiang
- Medical science monitor : international medical…
- 24 December 2015
Background We aimed to investigate the association of rheumatoid arthritis (RA) with interleukin 6 (IL-6) and tumor necrosis factor-α (TNF-α) through a meta-analysis. Material/Methods The… Expand
Expression of Survivin Gene and Its Relationship with Clinical Multidrug Resistance in Osteosarcoma
AbstractObjective: To study the expression of survivin and its relationship with clinical multidrug resistance in osteosarcoma. Methods: By using immunohistochemistry (S-P) method, the expression of… Expand
Knockdown of Collagen Triple Helix Repeat Containing-1 Inhibits the Proliferation and Epithelial-to-Mesenchymal Transition in Renal Cell Carcinoma Cells.
Collagen triple helix repeat containing-1 (CTHRC1), a secreted glycoprotein, is frequently upregulated in human cancers. However, the functional role of CTHRC1 in renal cell carcinoma (RCC) remains… Expand
MicroRNA‑613 inhibits proliferation and invasion of renal cell carcinoma cells through targeting FZD7.
- H. Song, Yonghao Nan, X. Wang, G. Zhang, Shi Zong, X. Kong
- Biology, Medicine
- Molecular medicine reports
- 1 October 2017
MicroRNAs (miRNAs) have emerged as critical regulators in cancer progression. miR‑613 has been reported as a tumor suppressor gene in many types of human cancers. However, the function of miR‑613 in… Expand
Correlation between IL-4 gene polymorphismas well as its mRNA expressionand rheumatoid arthritis.
OBJECTIVE This study sought to explore the correlation between IL-4-590C/T polymorphism as well as mRNA expression and the occurrence of rheumatoid arthritis (RA). PATIENTS AND METHODS IL-4-590C/T… Expand
A novel method to identify hub pathways of rheumatoid arthritis based on differential pathway networks
The aim of the current study was to identify hub pathways of rheumatoid arthritis (RA) using a novel method based on differential pathway network (DPN) analysis. The present study proposed a DPN… Expand
miR-30d Induced Apoptosis by Targeting Sox4 to Inhibit the Proliferation, Invasion and Migration of Nephroblastoma
Background Wilms tumor (WT) is an embryonic malignant tumor, and its related mechanism is still unclear. microRNA (miR), as a short-chain non-coding RNA, has low expression in various tumors. In this… Expand
Graphical induced structured input / output models
A single nucleotide polymorphism, often abbreviated to SNP, is a variation in a single nucleotide that occurs at a specific position in the genome. Genetic Association Hypothesis testing aims at… Expand
Inhibitive effect of insulin-like growth factor binding protein-1 on proliferation of cultured human umbilical vein endothelial cells
- Shi Zong
Objective To study the biological activity of the human insulin like growth factor binding protein 1 (IGFBP 1) and insulin like growth factor (IGF 1) on endothelial cell proliferation. Methods The… Expand
Progress in the Research of Cancer related Imprinted Genes
- Shi Zong
Genomic imprinting is the epigenetic marking of a gene based on its parental origin,which results in monoallelic expression.Those genes with this feature are classified as imprinted genes.Their… Expand