Shi Tian

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Gonadotropin-releasing hormone (GnRH) is a key regulator of reproductive maturation in humans and other vertebrates. Homologs of GnRH and its cognate receptor have been identified in invertebrates-for example, the adipokinetic hormone (AKH) and corazonin (CRZ) neuropeptide pathways in arthropods. However, the precise evolutionary relationships and origins(More)
MiR-98 expression was up-regulated in kidney in response to early diabetic nephropathy in mouse and down-regulated in muscle in type 2 diabetes in human. However, the expression prolife and functional role of miR-98 in human gestational diabetes mellitus (GDM) remained unclear. Here, we investigated its expression and function in placental tissues from GDM(More)
Neuropeptides are an ancient class of neuronal signaling molecules that regulate a variety of physiological and behavioral processes in animals. The life cycle of many animals includes a larval stage(s) that precedes metamorphic transition to a reproductively active adult stage but, with the exception of Drosophila melanogaster and other insects, research(More)
MicroRNA-10a (miR-10a) has a wide range of functions in nearly all mammalian tissues and is involved in the occurrence of many diseases. However, it remains unknown whether miR-10a is associated with human recurrent spontaneous abortion (RSA). In this study, we found that rs3809783 A > T in miR-10a coding region was significantly associated with the(More)
Computed tomography (CT) radiation dose can be reduced significantly by region of interest (ROI) CT scan. Automatically positioning the heart in CT scout images is an essential step to realize the ROI CT scan of the heart. This paper proposed a fully automatic heart positioning method in CT scout image, including the anteroposterior (A-P) scout image and(More)
The rigid registration is a key step of Image Guided Surgery (IGS), and the point-pair method is the main way used for registration. However the configuration of fiducial points has a great influence on the registration accuracy at the target point. Now almost all the optimization method of fiducial points configuration relies on the empirical(More)
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