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This paper establishes that recombination drives the evolution of GC content in a significant way. Because the human P-arm pseudoautosomal region (PAR1) has been shown to have a high recombination rate, at least 20-fold more frequent than the genomic average of approximately 1 cM/Mb, this region provides an ideal system to study the role of recombination in(More)
Investigator of Systems Bioinformatics. I completed a 3 years stay there and returned to the US in 2009. To summarize, my professional research career consists of three stages: Mathematics, Artificial Intelligence, and Computational Biology. These three fields has reinforced each other, and I have really been blessed by the interaction with many talented(More)
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