Sherry Perkins

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BACKGROUND Increased total homocysteine (tHcy) may be associated with placental-mediated adverse pregnancy outcomes, but few prospective studies have measured tHcy before pregnancy outcome. This study was undertaken to determine whether increased tHcy measured in early pregnancy is associated with pregnancy loss, gestational hypertension (GH), preeclampsia,(More)
One-carbon metabolism is a network of metabolic pathways, disruption of which has been associated with cancer and other pathological conditions. Biomarkers of these pathways include homocysteine (HCY), S-adenosylmethionine (SAM), and S-adenosylhomocysteine (SAH). A better understanding of the relationships between these biomarkers is needed for their(More)
Studies of technical work in healthcare offer prospects for developing deep understanding of the conflicts, demands, hazards, and opportunities that shape healthcare work. Efforts to produce this deep understanding are underway at several centers and employ a variety of methods including ethnographic research, studies of cognitive artifacts, and video(More)
The Lower North Shore region of the St. Lawrence River is home to a fish-eating population that displays an unusually high body burden of several organochlorines, including polychlorinated biphenyls (PCBs) and dioxin-like compounds (DLCs). We measured biomarkers indicative of liver enzyme induction and investigated the relationship with organochlorine body(More)
BACKGROUND In 2009 the Ontario Ministry of Health and Long Term Care funded the implementation of province-wide fetal fibronectin testing in Ontario hospitals. This paper reports results from the provincial evaluation that sought to describe the experience of fetal fibronectin testing from the perspective of women with symptoms of preterm labour. METHODS(More)
This prospective cohort study designed to assess the effect of folic acid supplementation in pregnancy on the risk of preeclampsia (PE) took place in Ottawa, ON and Kingston, ON, Canada, from September 1, 2002 to August 31, 2008. Pregnant women, less than 20 weeks gestational age were recruited and delivered in the Ottawa region and the Kingston General(More)
For anyone working in the field of trauma and PTSD, the role of substance use and abuse may seem obvious. Yet despite the prevalence and clinical significance of substance use disorders in individu­ als with PTSD, relatively little is actually known about the comorbidity of these disorders. The ma­ jority of published papers on this topic are based on(More)
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