Sherrina N Dixon

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When 54MnCl2 was incubated with fresh bovine or caprine serum for 20 h and the serum subjected to electrophoresis at pH 9.5, the 54Mn bound to transferrin and alpha2-macroglobulin in proportions which varied with the temperature of incubation and the temperature of electrophoresis. Between 0 and 37 degrees C, the higher the temperature of incubation the(More)
PURPOSE The purpose of this study was to determine whether cholesterol, the host cell receptor for pneumolysin of Streptococcus pneumoniae, could effectively treat pneumococcal keratitis. METHODS New Zealand White rabbits were intrastromally injected with 10(5) colony-forming units (CFUs) of S. pneumoniae D39. Corneas were treated with topical drops of 1%(More)
Influenza A virus evolution in humans is driven at least in part by mutations allowing the virus to escape antibody neutralization. Little is known about the evolution of influenza in birds, a major reservoir of influenza A. Neutralizing polyclonal antiserum was raised in chicken against reassortant influenza virus, CalX, bearing the hemagglutinin (HA) and(More)
PURPOSE The purpose of this study was to determine whether active immunization against pneumolysin (PLY), or polysaccharide capsule, protects against the corneal damage associated with Streptococcus pneumoniae keratitis. METHODS New Zealand White rabbits were actively immunized with Freund's adjuvant mixed with pneumolysin toxoid (ψPLY), Pneumovax 23(More)
INTRODUCTION In Great Britain i t has been estimated that 20% of all beef cattle are implanted with anabolic agents. The agents may be classified according to their mode of action; oestrogens, androgens, progestagens and anti-microbial compounds. The majority of implants are oestrogenic compounds, ie. substances with physiological properties similar to(More)
A competitive enzyme immunoassay (EIA) for the detection and quantitation of zeranol has been developed. The assay involves the use of excess second antibody adsorbed onto the walls of a microtitration plate well. Enzyme-labelled zeranol, prepared by the N-succinimidyl ester method, and standard or samples are added to the wells followed by zeranol-specific(More)
Cows of normal reproductive history were treated with progesterone for periods of 2--3 months. The uterine secretions yielded 5 major fractions of macromolecular components. Two of the fractions comprised serum proteins. In the other 3 fractions at least 9 non-serum proteins were observed, 7 in one fraction, but in only small amounts. Of the remaining 2(More)
Proteolytic digests of liver plasma-cell membranes from the cow were fractionated to yield two homogeneous glycopeptides and a third preparation about 92% pure. The composition of the two homogeneous glycopeptides made it clear that they were derived from basement membrane material rather than the plasma membrane. Ruminants are unusual in having large(More)
but essential (Beier, 1974). Culture studies in vitro with single protein fractions as supplements to the medium, or with non-fractionated uterine secretion proteins, indicate that single fractions (as uteroglobin) are not regulating blastocyst development alone, but it is evident that a regulatory system of several components is acting here (Maurer &(More)