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  • Kelly L Drew, C. Loren Buck, Brian M. Barnes, Sherri L. Christian, Brian T. Rasley, Michael S Harris
  • Biology, Medicine
  • Journal of neurochemistry
  • 2007 (First Publication: 1 September 2007)
  • Torpor during hibernation defines the nadir of mammalian metabolism where whole animal rates of metabolism are decreased to as low as 2% of basal metabolic rate. This capacity to decrease profoundlyContinue Reading
  • Austin P Ross, Sherri L. Christian, Huiwen W. Zhao, Kelly L Drew
  • Biology, Medicine
  • Journal of cerebral blood flow and metabolism…
  • 2006 (First Publication: 1 September 2006)
  • Hibernating Arctic ground squirrel (hAGS), Spermophilus parryii, survive profound decreases in cerebral perfusion during torpor and return to normal blood flow during intermittent rewarming periodsContinue Reading
  • Huiwen W. Zhao, Austin P Ross, Sherri L. Christian, John N Buchholz, Kelly L Drew
  • Medicine, Biology
  • Journal of neuroscience research
  • 2006 (First Publication: 1 August 2006)
  • Heterothermic mammals such as ground squirrels tolerate ischemia and N-methyl-D-aspartate (NMDA) better than homeothermic mammals such as rats both in vivo and in vitro, and this tolerance isContinue Reading
  • Sherri L. Christian, Austin P Ross, +5 authors Kelly L Drew
  • Biology, Medicine
  • Journal of cerebral blood flow and metabolism…
  • 2008 (First Publication: 1 July 2008)
  • Oxygen—glucose deprivation (OGD) initiates a cascade of intracellular responses that culminates in cell death in sensitive species. Neurons from Arctic ground squirrels (AGS), a hibernating species,Continue Reading
  • Huiwen W. Zhao, Sherri L. Christian, Marina R. Castillo, Abel Bult-Ito, Kelly L Drew
  • Biology, Medicine
  • Journal of Chemical Neuroanatomy
  • 2006 (First Publication: 1 December 2006)
  • Hibernation is a natural model of neuroprotection and adult synaptic plasticity. NMDA receptors (NMDAR), which play key roles in excitotoxicity and synaptic plasticity, have not been characterized inContinue Reading
  • Sherri L. Christian, Brian T. Rasley, Tanna Roe, Jeanette T. Moore, Michael Brennan Harris, Kelly L Drew
  • Biology, Medicine
  • Front. Physiol.
  • 2014 (First Publication: 9 May 2014)
  • Hibernation is a unique physiological adaptation characterized by periods of torpor that consist of repeated, reversible, and dramatic reductions of body temperature, metabolism, and blood flow.Continue Reading