Sherif F. Nagueh

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Sherif F. Nagueh, MD, Chair, Christopher P. Appleton, MD, Thierry C. Gillebert, MD,* Paolo N. Marino, MD,* Jae K. Oh, MD, Otto A. Smiseth, MD, PhD,* Alan D. Waggoner, MHS, Frank A. Flachskampf, MD, Co-Chair,* Patricia A. Pellikka, MD, and Arturo Evangelista, MD,* Houston, Texas; Phoenix, Arizona; Ghent, Belgium; Novara, Italy; Rochester, Minnesota; Oslo,(More)
OBJECTIVES This investigation was designed 1) to assess whether the early diastolic velocity of the mitral annulus (Ea) obtained with Doppler tissue imaging (DTI) behaves as a preload-independent index of left ventricular (LV) relaxation; and 2) to evaluate the relation of the mitral E/Ea ratio to LV filling pressures. BACKGROUND Recent observations(More)
Echocardiographic imaging is ideally suited for the evaluation of cardiac mechanics because of its intrinsically dynamic nature. Because for decades, echocardiography has been the only imaging modality that allows dynamic imaging of the heart, it is only natural that new, increasingly automated techniques for sophisticated analysis of cardiac mechanics have(More)
Sherif F. Nagueh, Chair, MD, FASE, Otto A. Smiseth, Co-Chair, MD, PhD, Christopher P. Appleton, MD, Benjamin F. Byrd, III, MD, FASE, Hisham Dokainish, MD, FASE, Thor Edvardsen, MD, PhD, Frank A. Flachskampf, MD, PhD, FESC, Thierry C. Gillebert, MD, PhD, FESC, Allan L. Klein, MD, FASE, Patrizio Lancellotti, MD, PhD, FESC, Paolo Marino, MD, FESC, Jae K. Oh,(More)
Methodology...... ..............................................1021 Imaging Equipment and Technique............1021 Stress Testing Methods...... ............................1022 Training Requirements and Maintenance of Competency...... .....................................1023 Image Interpretation......................................1024 Table 1. Normal(More)
Background—The role of the giant protein titin in patients with heart failure is not well established. We investigated titin expression in patients with end-stage heart failure resulting from nonischemic dilated cardiomyopathy, in particular as it relates to left ventricular (LV) myocardial stiffness and LV function. Methods and Results—SDS-agarose gels(More)
AIMS To examine myocardial deformation and rotation in patients with heart failure, and elucidate the underlying mechanisms that account for normal ejection fraction (EF) in patients with diastolic heart failure (DHF). METHODS AND RESULTS Fifty consecutive patients presenting with congestive heart failure (age: 58 +/- 16 years) underwent simultaneous(More)
BACKGROUND Early transmitral velocity/tissue Doppler mitral annular early diastolic velocity (E/Ea) and B-type natriuretic peptide (BNP) have been correlated with left ventricular filling pressures, yet there are no data on how these 2 estimates of left ventricular filling pressures compare. METHODS AND RESULTS Patients admitted to intensive care(More)