Shereen Zulfiqar Bhutta

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Several recent reviews of maternal, newborn, and child health (MNCH) and mortality have emphasised that a large range of interventions are available with the potential to reduce deaths and disability. The emphasis within MNCH varies, with skilled care at facility levels recommended for saving maternal lives and scale-up of community and household care for(More)
BACKGROUND Maternal micronutrient deficiencies are widespread in Pakistan and are potentially associated with maternal undernutrition and intrauterine growth retardation. Intervention strategies largely consist of administration of iron-folic acid supplements during pregnancy. OBJECTIVE We evaluated the acceptability of multiple micronutrient(More)
OBJECTIVE To determine the effect of partogram on the frequency of prolonged labour, augmented labour, operative deliveries and whether appropriate interventions based on the partogram will reduce maternal and perinatal complications. METHOD A case controlled, prospective and interventional study on 1000 women in labour was carried out in the obstetric(More)
BACKGROUND Pre-eclampsia/eclampsia are leading causes of maternal mortality and morbidity, particularly in low- and middle- income countries (LMICs). We developed the miniPIERS risk prediction model to provide a simple, evidence-based tool to identify pregnant women in LMICs at increased risk of death or major hypertensive-related complications. METHODS(More)
Globally, Pakistan has the third highest burden of maternal, fetal, and child mortality. It has made slow progress in achieving the Millennium Development Goals (MDGs) 4 and 5 and in addressing common social determinants of health. The country also has huge challenges of political fragility, complex security issues, and natural disasters. We undertook an(More)
OBJECTIVE To determine the efficacy of single dose of magnesium sulphate versus the standard Pritchard regime in the management of pre-eclampsia. STUDY DESIGN Quasi-experimental study. PLACE AND DURATION OF STUDY Jinnah Postgraduate Medical Centre, Karachi, from January 2004 to January 2006. METHODOLOGY All women with severe pre-eclampsia and(More)
OBJECTIVE To determine the frequency of induced abortion and identify the role of sociocultural factors contributing to termination of pregnancy and associated morbidity and mortality in hospital setting. DESIGN Prospective observational study. PLACE AND DURATION OF STUDY The study was conducted in the Department of Obstetrics and Gynaecology, Jinnah(More)
OBJECTIVE To perform culture and sensitivity for pathogens causing puerperal and postoperative wound sepsis and determine the frequency of Methicillin Resistant Staphylococcus aureus (MRSA) in such infections. STUDY DESIGN Observational study. PLACE AND DURATION OF STUDY Obstetrics and Gynaecology Ward, Jinnah Postgraduate Medical Centre, Karachi, from(More)
BACKGROUND Our objective was to estimate the effect of various childbirth care packages on neonatal mortality due to intrapartum-related events ("birth asphyxia") in term babies for use in the Lives Saved Tool (LiST). METHODS We conducted a systematic literature review to identify studies or reviews of childbirth care packages as defined by United Nations(More)
OBJECTIVE To examine the ability of three different proteinuria assessment methods (urinary dipstick, spot urine protein:creatinine ratio [Pr/Cr], and 24-hour urine collection) to predict adverse pregnancy outcomes. METHODS We performed a prospective multicentre cohort study, PIERS (Preeclampsia Integrated Estimate of RiSk), in seven academic tertiary(More)