Shenwei Zhang

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Apelin, a cytokine mainly secreted by adipocytes, is closely related with insulin resistance. The underlying molecular mechanisms of how apelin affects insulin resistance, however, are poorly understood. This study aimed to investigate the effect of apelin on glucose metabolism and insulin resistance in 3T3-L1 adipocytes. After 10 ng/ml TNF-α treatment for(More)
Cardiac microvascular endothelial cells (CMECs) dysfunction induced by hypoxia is an important pathophysiological event in myocardium ischemic injury, whereas, the underlying mechanism is not fully clarified. FoxO transcription factors regulate target genes involved in apoptosis and cellular reactive oxygen species (ROS) production. Therefore, the present(More)
This paper describes the use of the second-order polynomial dynamic linear model (DLM) to characterize the growth of the depth of corrosion defects on energy pipelines using data obtained from multiple high-resolution in-line inspections (ILI). The growth model incorporates the measurement error of the ILI tools and captures the temporal variability of the(More)
Unmanned aerial vehicles have some characteristics such as strong flexibility and lower costs that are suitable for capturing information in special scenarios and environments. Collaborative working of multi-UAV system is an important performance metric for mobile computing in wireless networks. Ant Colony Algorithm is a dynamic path selecting optimization(More)
Cardiac microvascular endothelial cells (CMECs) dysfunction is an important pathophysiological event in the cardiovascular complications induced by diabetes. However, the underlying mechanism is not fully clarified. Autophagy is involved in programmed cell death. Here we investigated the potential role of autophagy on the CMECs injury induced by high(More)
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