Shengnan Zhang

Paul F. Fitzpatrick2
Lingyan Liang1
2Paul F. Fitzpatrick
1Lingyan Liang
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PURPOSE To investigate the effect of the B and T lymphocyte attenuator (BTLA; CD272) on cluster of differentiation (CD)4(+) T cell-mediated corneal immunopathology during murine herpetic stromal keratitis (HSK). METHODS BALB/c mice were infected with the herpes simplex virus type 1 (HSV-1) KOS strain by corneal scarification. The levels of BTLA expression(More)
Analytical ultracentrifugation has been used to analyze the oligomeric structure of the isolated regulatory domain of phenylalanine hydroxylase. The protein exhibits a monomer-dimer equilibrium with a dissociation constant of ~46 μM; this value is unaffected by the removal of the 24 N-terminal residues or by phosphorylation of Ser16. In contrast,(More)
Sub-gap density of states (DOS) is a key parameter to impact the electrical characteristics of semiconductor materials-based transistors in integrated circuits. Previously, spectroscopy methodologies for DOS extractions include the static methods, temperature dependent spectroscopy and photonic spectroscopy. However, they might involve lots of assumptions,(More)
Heortia vitessoides Moore is the most destructive defoliator of Aquilaria sinensis (Loureiro) Sprenger, an endangered and economically important plant that produces the high-prized agarwood. After maturing, H. vitessoides larvae will leave the A. sinensis and pupate in soil, however, factors affecting this behavior have not been previously addressed. In the(More)
Liver phenylalanine hydroxylase is allosterically activated by phenylalanine. The structural changes that accompany activation have not been identified, but recent studies of the effects of phenylalanine on the isolated regulatory domain of the enzyme support a model in which phenylalanine binding promotes regulatory domain dimerization. Such a model(More)
Considering the strong inhomogeneous spatial polarization and intensity distribution of spontaneous decay fluorescence due to the Hanle effect, we propose and demonstrate a universe Hanle detection configuration of electron-shelving method for optical clocks. Experimental results from Ca atomic beam optical frequency standard with electron-shelving method(More)
—A fast method of detecting and automatic marking ellipses in the circle array target image sequences with high quality and strong regular pattern is proposed in this paper. This method collects a small amount of edge points from the ellipse by directly scanning the target image and searching for jumpy-changing of pixels, which can be used to identify the(More)