Shenghui Huang

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OBJECTIVE To investigate the influence of anastomotic leakage (AL) on long-term survival after resection for rectal cancer. METHODS Clinicopathological data of 653 rectal cancer cases confirmed by pathology and undergoing R0 resection for rectal cancer in our department from January 2007 to December 2011 were retrospectively analyzed. Anastomotic leakage(More)
OBJECTIVE We examined the whole genome expression profile in advanced colorectal cancer (ACC) patients who had received FOLFOX4 chemotherapy to establish a genetic biomarker model predicting chemotherapy sensitivity. METHODS Eligible ACC patients were divided into two groups, based on postchemotherapy evaluation results: specifically, the sensitive group(More)
OBJECTIVE To explore predictive factors associated with pathologic complete response (pCR) after neoadjuvant chemoradiotherapy for rectal cancer. METHODS Clinicopathological data of 163 patients with locally advanced rectal cancer who were treated with neoadjuvant chemoradiotherapy followed by radical surgical resection from January 2007 to May 2013 were(More)
In order to study the feasibility on heat storage of underground concrete, this paper set up the mathematical model on thermal storage of underground concrete pile. And it adopted ANSYS finite element analysis software to numerically simulate the temperature field of underground concrete pile. The analysis showed that: during the period of heat storage, the(More)
OBJECTIVE To establish a nomogram to predict long-term survival in non-metastatic colorectal cancer patients. METHODS A retrospective analysis was conducted in patients with non-metastatic colorectal cancer who underwent radical surgery in the Department of Colorectal Surgery of Affiliated Union Hospital of Fujian Medical University between January 2000(More)
OBJECTIVE To clarify the natural course and explore impact factors of distant metastasis in rectal cancer patients who received total mesorectal excision(TME) following neoadjuvant chemoradiotherapy (CRT). METHODS Between Januray 2008 and December 2013, 317 patients with locally advanced rectal cancer who underwent radical surgical resection following(More)
OBJECTIVE To investigate the effect of intestinal resection on hydrogen sulfide (H2S) biosynthesis and interstitial cells of Cajal(ICC) in mice. METHODS After intestinal resection mouse model was established, the activity of MPO in the proximal anastomosis intestinal tissue were detected. Sensitive sulphur electrode assay was applied to measure the H2S(More)
PURPOSE To determine predictors of pathological complete response (pCR) in locally advanced rectal cancer patients treated with neoadjuvant chemoradiotherapy (nCRT), and develop a predictive nomogram. METHODS A total of 522 locally advanced rectal cancer patients undergoing nCRT and curative resection between 2008 and 2014 were included. Uni- and(More)
OBJECTIVE To explore the risk factors of anal function after transabdominal intersphincteric resection(ISR) for low rectal cancer. METHODS Clinical and follow-up data of 96 patients with low rectal cancer who underwent transabdominal ISR in our department from January 2005 to December 2012 were analyzed retrospectively. The Wexner scoring scale was used(More)
PURPOSE To compare distant metastasis (DM) in locally advanced rectal cancer (LARC) patients treated with neoadjuvant chemoradiotherapy (nCRT) and surgery alone, and to develop a predictive nomogram for DM following nCRT. METHODS Propensity-scoring match analysis was performed to compare DM in LARC treated with nCRT (n = 375) and surgery alone (n = 375).(More)