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Trigochinins A-C: three new daphnane-type diterpenes from Trigonostemon chinensis.
This study suggested the revision of the C-6 stereochemistry of trigonothyrins A-C reported quite recently, which showed significant inhibition against MET tyrosine kinase activity. Expand
Alkaloids from Gelsemium elegans.
Compounds 1-4 were evaluated for cytotoxic activity against four tumor cell lines, and gelsebamine selectively inhibited the A-549 human lung adenocarcinoma cell line. Expand
Antifungal diterpenoids of Pseudolarix kaempferi, and their structure-activity relationship study.
The in vitro antifungal activities of 19 structurally diversified analogues of pseudolaric acids tested against the major pathogenic fungus Candida albicans has led to the establishment of a veryExpand
Agladupols A-E, triterpenoids from Aglaia duperreana.
A (13)C NMR-based general rule for assignment of the C-21 configuration in the side chain of apotirucallane- and tiruc allane-type triterpenoids was proposed and the relative stereochemistry of 21- O-methyltoosendanpentol (1a), a known compound with the relative configurations of the stereocenters in theSide chain undetermined, was completely assigned. Expand
Chlorahololides A and B, two potent and selective blockers of the potassium channel isolated from Chloranthus holostegius.
Chlorahololides A (1) and B (2) exhibited potent and selective inhibition on the delayed rectifier K+ current, with an IC50 of 10.9 and 18.6 microM, respectively. Expand
Daphniyunnines A-E, alkaloids from Daphniphyllum yunnanense.
The first chemical study on the stems and leaves of Daphniphyllum yunnanense led to the isolation of five new alkaloids, daphniyunnines A-E (1-5). Daphniyunnines B-E (2-5) are four unusual C-22Expand
Cytotoxic sesquiterpenoids from Sarcandra glabra
Abstract Five new sesquiterpenoid dimers, sarcandrolides F−J (1−5), three new sesquiterpenoid monomers (6−8), and 14 known sesquiterpenoids, were isolated from the whole plants of Sarcandra glabra.Expand
Chuktabularins A-D, four new limonoids with unprecedented carbon skeletons from the stem bark of Chukrasia tabularis.
Chuktabularins A-D (1-4), four novel 16-norphragmalin-type limonoids that feature unprecedented skeletons with a biosynthetically extended C2 or C3 unit at C-15 forming a uniqueExpand
Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum.
Ten new guaiane type sesquiterpene lactones, namely, eupalinilides A-J, as well as nine known compounds, e upachinilide C, have been tested for cytotoxicity against P-388 and A-549 tumor cell lines and showed potent cytot toxicity. Expand
Eucarobustols A-I, Conjugates of Sesquiterpenoids and Acylphloroglucinols from Eucalyptus robusta.
Nine new conjugates of sesquiterpenoids and acylphloroglucinols, named eucarobustols A-I (1-9), as well as 11 known analogues were isolated from the leaves of Eucalyptus robusta, with inhibitory activities against protein tyrosine phosphatase 1B. Expand