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DNA methyltransferase 1 (DNMT1) catalyzes DNA methylation and is overexpressed in various human diseases, including cancer. A rational approach to preventing tumorigenesis involves the use of… Continue Reading
Lung and breast cancer are the leading causes of mortality in women worldwide. The discovery of molecular alterations that underlie these two cancers and corresponding drugs has contributed to… Continue Reading
OBJECTIVE To construct, express and identify the recombinant plasmid pcDNA3.1(+)/sflk1-IFN-gamma encoding bifunctional protein sflk1-IFN-gamma (soluble fetal liver kinase 1 and interferon-gamma). … Continue Reading
Colorectal cancer is a highly malignant process in gastrointestinal tract. It is associated with poor prognosis due to difficulty in early detection and highly mortality rate. Therefore, early… Continue Reading
The present study aimed to screen for dominant species involved in Baiyaojian fermentation based on the appearance and gallic acid content of Baiyaojian. The species were added via two routes: Jiuqu… Continue Reading
Gene silencing by aberrant DNA methylation of promoter regions remains the most dominant phenomenon occurring during tumorigenesis. Improving the early diagnosis, prognosis, and recurrence prediction… Continue Reading