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The purpose of these studies was to determine the role of gracile nucleus and the effects of l-arginine-derived nitric oxide (NO) synthesis in the nucleus on the cardiovascular responses to electroacupuncture (EA) stimulation of "Zusanli" (ST36). Arterial blood pressure and heart rate were monitored during EA stimulation of ST36 following microinjections of(More)
Recent studies have reported that l-arginine-derived nitric oxide (NO) in the gracile nucleus modifies the hypotensive responses to electroacupuncture (EA) stimulation of Zusanli (ST 36). The purpose of this study was to examine the influence of EA stimulation of ST 36 on neuronal NO synthase (nNOS) expression in the brainstem nuclei in rats. EA stimulation(More)
It has long been accepted that acupuncture, puncturing and scraping needles at certain points on the body, can have analgesic and anesthetic effects, as well as therapeutic effects in the treatment of various diseases. This therapy, including acupuncture anesthesia, has drawn the attention of many investigators and become a research subject of international(More)
The present study was to examine the distribution of transient receptor potential vanilloid type-1 (TRPV1) receptor immunoreactivity in the acupuncture points (acupoint), and determine the influences of electroacupuncture (EA) stimulation on TRPV1 expression. EA stimulation of BL 40 was conducted in two sessions of 20 min separated by an 80 min interval in(More)
These studies examined the influence of 2,5-hexanedione (2,5-HD) intoxication on expression of neuronal nitric oxide synthase (nNOS) in the brainstem nuclei in Zucker Diabetic Fatty (ZDF) vs. lean control (LC) rats. Functional neuropathic changes were also investigated following axonal damage and impaired axonal transport induced by the treatment. Animals(More)
This study was to examine the influence of electroacupuncture (EA) stimulation on neuronal nitric oxide synthase (nNOS) expression in the brainstem nuclei in rats. Low-frequency EA stimulation (3 pulses/sec) was applied between 2 acupuncture points (acupoints), Jinggu (BL 64) and Shugu (BL 65) which are cutaneously located at hindlimb, in rats anesthetized(More)
The annual North American Symposium on Acupuncture is the main scientific part of the educational program in Traditional Chinese Medicine (TCM) established by the Academy of Pain Research in 1979. Dr T. N. Lee, Founder and Director of the Academy and distinguished researcher who proposed the Thalamic Neuron Theory to explain the analgesic effects of(More)
This study examined the influence of age, gender and race on nitric oxide (NO) release over acupuncture points, meridian without acupoint, and non-meridian regions of the Pericardium (PC) and Bladder (BL) meridian as well as aging on LU meridian in 61 healthy subjects. Biocapture tubes were attached to the skin surface, and total nitrite and nitrate was(More)
The purpose of these studies was to examine the effects of electroacupuncture (EA) Zusanli (ST36) on release of nitric oxide (NO) in the gracile nucleus (GN) and determine if functional neuropathic changes were modified by EA ST36-induced NO in the nucleus in Zucker diabetic fatty (ZDF) rats. The foot withdrawal responses to mechanical, thermal and cold(More)
Activation of afferent cutaneous or mixed nerves, such as the sural or the sciatic, results in changes in sympathetic activity and arterial blood pressure by excitatory somatosympathetic reflexes (SSR). The underlying causes and modulation of SSR functions in the dorsal medulla are poorly understood. This review focuses our recent findings incorporated with(More)