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  • Qing-hai Zhang, Xuyu Zu, +8 authors Guang-hui Yi
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 2012 (First Publication: 1 March 2012)
  • It is well-known that sphingosine-1-phosphate (S1P), the phospholipid content of HDL, binding to S1P receptors can raise COX-2 expression and PGI(2) release through p38MAPK/CREB pathway. In theContinue Reading
  • Sheng-Lin Xiong, Xing Liu, Guang-hui Yi
  • Medicine, Biology
  • Molecular and Cellular Biochemistry
  • 2013 (First Publication: 1 April 2014)
  • High-density lipoprotein (HDL) has a significant cardioprotective effects. HDL induces cyclooxygenase-2 (COX-2) expression and prostacyclin I-2 (PGI-2) release in vascular endothelial cells, whichContinue Reading