Sheldon Y Freeberg

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We determined the effects of cyclooxygenase-1 (COX-1; SC-560), COX-2 (SC-58125), and inducible nitric oxide synthase (iNOS; 1400W) inhibitors on atorvastatin (ATV)-induced myocardial protection and whether iNOS mediates the ATV-induced increases in COX-2. Sprague-Dawley rats received 10 mg ATV.kg(-1).day(-1) added to drinking water or water alone for 3 days(More)
Objectives: We determined the effects of cycloxygenase-1 (COX1)(Sc560), COX2 (Sc58125) and inducible nitric oxide synthase (iNOS)(1400w) inhibitors on atorvastatin (ATV)-induced myocardial protection and whether iNOS mediates the ATV-induced increases in COX2. Methods: Sprague-Dawley rats received ATV 10 mg/kg/d added to the drinking water or water alone(More)
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