Shelby A Walters

Learn More
OBJECTIVE An experiment was conducted to test the hypothesis that feedback about an ADHD diagnosis influences how a nonclinical sample scores on the Adult ADHD Self-Report Scale (ASRS) screener. METHOD A total of 54 participants who scored below clinical significance on the ASRS in a pretest, that is, marked fewer than 4 of 6 items found to be most(More)
[3H]Choline mustard aziridinium ion binds irreversibly to the sodium-coupled high-affinity choline transport protein in a sodium-dependent and hemicholinium-sensitive manner, and thus is a useful affinity ligand. In rat striatal synaptosomal membranes, it radiolabels two polypeptides with apparent molecular masses of 58 and 35 kDa. Based upon the use of two(More)
Membrane carriers display structural and functional asymmetry with a substrate binding site which can be oriented alternately, but not simultaneously, to the extracellular and intracellular environment. Hemicholinium-3 is an inhibitor of the high-affinity choline carrier in cholinergic nerve terminals which binds to the transporter at the outer membrane(More)
The objective of this study was to measure the uptake and metabolism of [3H]choline mustard aziridinium ion in rat brain synaptosomes. In previous investigations, we showed that this compound binds irreversibly to the choline carrier thereby inhibiting choline transport into nerve terminals; it also acts as both a substrate and inhibitor of the(More)
  • 1