Sheila Shirley

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Noroviruses are the leading cause of epidemic acute gastroenteritis in the United States. From September 2009 through August 2013, 3,960 norovirus outbreaks were reported to CaliciNet. Of the 2,895 outbreaks with a known transmission route, person-to-person and food-borne transmissions were reported for 2,425 (83.7%) and 465 (16.1%) of the outbreaks,(More)
BACKGROUND Cases of rotavirus-associated acute gastroenteritis have declined since the introduction of rotavirus vaccines, but the burden of norovirus-associated acute gastroenteritis in children remains to be assessed. METHODS We conducted active surveillance for laboratory-confirmed cases of norovirus among children younger than 5 years of age with(More)
BACKGROUND Although rotavirus and norovirus cause nearly 40% of severe endemic acute gastroenteritis (AGE) in children <5 years of age in the United States, there are limited data on the etiologic role of other enteric viruses in this age group. METHODS We conducted active population-based surveillance in children presenting with AGE to hospitals,(More)
BACKGROUND Norovirus is a leading cause of acute gastroenteritis (AGE). Noroviruses bind to gut histo-blood group antigens (HBGAs), but only 70%-80% of individuals have a functional copy of the FUT2 ("secretor") gene required for gut HBGA expression; these individuals are known as "secretors." Susceptibility to some noroviruses depends on FUT2 secretor(More)
Two methods of processing cerebrospinal fluid (CSF) cells for morphologic study were compared. The newer cytocentrifugation method, using the Shandon Cytospin apparatus, allowed slightly quicker processing of cells but did not appreciably influence the total time needed to fully study the cells. The preservation of cells, as measured by observation of(More)
An estimated 179 million acute gastroenteritis (AGE) illnesses occur annually in the United States. The role of noroviruses in hospital-related AGE has not been well-documented in the U. S. We estimated the population incidence of community- acquired outpatient and inpatient norovirus AGE encounters, as well as hospital-acquired inpatient norovirus AGE(More)
Improving tropical maize (Zea mays L.) tolerance for drought s tress was initiated i n 1991 i n a fullsib recurrent selection program. This breeding program was initiated to compare two selection environments and to improve the yield stability of tropical maize under the north Florida drought-prone environments. Rainfed and irr igated plots were used to(More)
An estimated 179 million acute gastroenteritis (AGE) illnesses occur annually in the United States. The role of noroviruses in hospital-related AGE has not been well-documented in the U. S. We estimated the population incidence of communityacquired outpatient and inpatient norovirus AGE encounters, as well as hospital-acquired inpatient norovirus AGE among(More)
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