Shay P Heaton

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Background:The Ras/RAF/MEK/ERK pathway is frequently deregulated in cancer and a number of inhibitors that target this pathway are currently in clinical development. It is likely that clinical testing of these agents will be in combination with standard therapies to harness the apoptotic potential of both the agents. To support this strategy, it has been(More)
PURPOSE To show the signal intensity varies with shot number in diffusion-weighted (DW) echo-planar imaging (EPI) and affects apparent diffusion coefficient (ADC) calculation. MATERIALS AND METHODS This prospective study was performed on 35 adult patients and 20 volunteers. Measurements were made on a 3T scanner using a breathhold DW spin-echo EPI (SE(More)
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