Shawn Zimmerman

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BACKGROUND Patients with familial adenomatous polyposis have a nearly 100 percent risk of colorectal cancer. In this disease, the chemopreventive effects of nonsteroidal antiinflammatory drugs may be related to their inhibition of cyclooxygenase-2. METHODS We studied the effect of celecoxib, a selective cyclooxygenase-2 inhibitor, on colorectal polyps in(More)
CASE DESCRIPTION A 1.5-year-old mixed-breed dog was examined because of a 1-month history of anorexia, vomiting, diarrhea, and weight loss. CLINICAL FINDINGS The dog was very thin on physical examination (body condition score, 3/9). Results of all diagnostic tests were within reference limits except intestinal thickening and lymphadenopathy were(More)
BACKGROUND Non-selective cyclooxygenase (COX) inhibitors (non-steroidal anti-inflammatory drugs) inhibit large bowel carcinogenesis in patients with familial adenomatous polyposis (FAP). Their role in the duodenum of these patients is less certain. The disease modifying activity of specific COX-2 inhibitors has not been explored in humans. PATIENTS AND(More)
A prospective longitudinal study of shoulder function after 103 neck dissections involving either preservation or sacrifice of the spinal accessory nerve is presented. The postoperative evolution and course of trapezius muscle denervation and resultant shoulder dysfunction were objectively determined for both radical and modified nerve sparing neck(More)
A 14-year-old boy with no history of transfusion experienced a hemolytic crisis attributed to paroxysmal cold hemoglobinuria. The Donath-Landsteiner test was positive. The IgG autoantibody had anti-P specificity but was unique in that it also reacted strongly by indirect antiglobulin test at 37 degrees C.
Page kidney is the name ascribed to a rare syndrome of hyperreninemic hypertension caused by unilateral compressive perinephritis. Blood or fluid that accumulates in the perinephric subcapsular space compresses the renal parenchyma leading to ischemia. This syndrome is analogous to the description of cellophane-induced perinephritis by Page in 1939. Page(More)
The subsequent urine sample did not contain these agents. Numerous Giardia cysts were detected by fluorescent antibody staining of the feces. Sediment examination of ‘‘urine’’ collected by cystocentesis from an adult female spayed dog presenting for diarrhea. x100 objective. (Left) Giardia spp. trophozoite and scattered bacterial rods and cocci. (Right,(More)