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Nuclear pore complexes (NPCs) gate the only conduits for nucleocytoplasmic transport in eukaryotes. Their gate is formed by nucleoporins containing large intrinsically disordered domains with multiple phenylalanine-glycine repeats (FG domains). In combination, these are hypothesized to form a structurally and chemically homogeneous network of random coils(More)
BACKGROUND Molecular dynamics (MD) simulation is a powerful technique for sampling the meta-stable and transitional conformations of proteins and other biomolecules. Computational data clustering has emerged as a useful, automated technique for extracting conformational states from MD simulation data. Despite extensive application, relatively little work(More)
We describe recent research into using the visual primitive of texture to analyze and manage large collections of remote sensed image and video data. Texture is regarded as the spatial dependence of pixel intensity. It is characterized by the amount of dependence at different scales and orientations, as measured with frequency-selective filters. A(More)
This paper describes a framework for applying traditional data mining techniques to the non-traditional domain of image datasets for the purpose of knowledge discovery. In particular, perceptual association rules, a novel extension of traditional association rules, are used to distill the frequent perceptual events in large image datasets in order to(More)
Detection and tracking of moving objects is important in the analysis of video data. One approach is to maintain a background model of the scene and subtract it from each frame to detect the moving objects which can then be tracked using Kalman or particle filters. In this paper, we consider simple techniques based on salient points to identify moving(More)
Object based representations of tmage data enable nev, content-related funcuonahtles whde facditatmg management of large tmage databases. Developing such representations for multi-date and muhl-spectral tmages is one of the objectwes of the second phase of the Alexandrm Digital Library (ADL) project at UCSB. Image segmentation and ~mage reg~strauon are two(More)
Continuing improvements in algorithms and computer speeds promise that an increasing number of biomolecu-lar phenomena can be simulated by molecular dynamics to produce accurate " trajectories " of their molecular motions on the nanosecond to microsecond time scale. An important target for such simulations will be non-equilibrium biochemical processes, such(More)
We investigate publicly available geo-referenced photo collections for land cover classification. Mapping land cover is a fundamental task in the geographic sciences and is typically done using remote sensing (overhead) imagery through manual annotation. We here propose a novel alternate approach based on proximate sensing. The goal of proximate sensing is(More)