Shaunak Kamat

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Hyperactivated DEG/ENaCs induce neuronal death through excessive cation influx and disruption of intracellular calcium homeostasis. Caenorhabditis elegans DEG/ENaC MEC-4 is hyperactivated by the (d) mutation and induces death of touch neurons. The analogous substitution in MEC-10 (MEC-10(d)) co-expressed in the same neurons is only mildly neurotoxic. We(More)
Limiting the debilitating consequences of ageing is a major medical challenge of our time. Robust pharmacological interventions that promote healthy ageing across diverse genetic backgrounds may engage conserved longevity pathways. Here we report results from the Caenorhabditis Intervention Testing Program in assessing longevity variation across 22(More)
Welcome to the 5 th Annual Graduate Student Symposium hosted by Joint Molecular Biosciences Graduate Student Association (JMBGSA) of UMDNJ/Rutgers University. We are delighted that you are joining us today to promote and support graduate student research. The work performed by our graduate student community contributes significantly to scientific(More)
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