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Circadian rhythm mechanisms involve multi-scale interactions between endogenous DNA-transcription oscillators. We present the application of efficient, numerically well-conditioned algorithms for abstracting (potentially large) systems of differential equation models of circadian oscillators into compact, accurate phase-only macromodels. We apply and(More)
Circadian rhythm mechanisms involve multi-scale interactions between endogenous DNA-transcription oscillators. We present the application of efficient, numerically well-conditioned algorithms for abstracting (potentially large) systems of differential equation models of circadian oscillators into compact, accurate phase-only macromodels. We apply and(More)
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