Sharon R Green

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The RNA-binding domain of the protein kinase DAI, the double-stranded RNA inhibitor of translation, contains two repeats of a motif that is also found in a number of other RNA-binding proteins. This motif consists of 67 amino acid residues and is predicted to contain a positively charged alpha helix at its C terminus. We have analyzed the effects of(More)
The interferon-induced, dsRNA-activated human protein kinase (PKR) exerts antiviral and antiproliferative effects through inhibition of protein synthesis. Studies of structure-function relationships in PKR have shown that two dsRNA binding motifs are important for its autophosphorylation and activation by dsRNA in vitro. To correlate these findings with the(More)
In 1971, I made a film entitled Self Portrait of a Nude Model Turned Cinematographer in which I explore the objectifying 'male' gaze on my body in contrast to the subjective lived experience of my body. The film was a radical challenge to the gaze that objectifies woman - and thus imprisons her - which had hitherto dominated narrative cinema. Since the(More)
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