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  • Michael Bruce Bolger, Ian S. Haworth, +8 authors Vincent H L Lee
  • Chemistry, Medicine
  • Journal of pharmaceutical sciences
  • 1998 (First Published: 1 November 1998)
  • The proton-coupled intestinal dipeptide transporter, PepT1, has 707 amino acids, 12 putative transmembrane domains (TMD), and is of importance in the transport of nutritional di- and tripeptides andContinue Reading
  • A K Yeung, Sandip K. Basu, +10 authors Vincent H L Lee
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 1998 (First Published: 1 September 1998)
  • hPepT1 is a proton-coupled peptide transporter that mediates the absorption of di- and tripeptides. Here we show that tyrosine 167 (Y167) in transmembrane domain 5 (TMD5) of this 12-transmembraneContinue Reading
  • Vincent H L Lee, C C Chu, +8 authors Curtis T. Okamoto
  • Chemistry, Medicine
  • Journal of controlled release : official journal…
  • 1999 (First Published: 1 November 1999)
  • Non-invasive delivery of peptide and protein drugs will soon become a reality. This is due partly to a better understanding of the endogenous transport mechanisms, including paracellular transport,Continue Reading