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Chitinases help plants defend themselves against fungal attack, and play roles in other processes, including development. The catalytic modules of most plant chitinases belong to glycoside hydrolase family 19. We report here x-ray structures of such a module from a Norway spruce enzyme, the first for any family 19 class IV chitinase. The bi-lobed structure(More)
PURPOSE To investigate the relationship between functional phenotype of and the associated human corneal infection. METHODS This was an experimental pilot study of patients presenting with corneal infections at the Jules Stein Eye Institute with presumed infection during the period from 12/30/97 to 9/1/00. Thirteen patients were admitted to the study(More)
Brassica juncea chitinase is an endo-acting, pathogenesis-related protein that is classified into glycoside hydrolase family 19, with highest homology (50-60%) in its catalytic domain to class I plant chitinases. Here we report X-ray structures of the chitinase catalytic domain from wild-type (apo, as well as with chloride ions bound) and a Glu234Ala mutant(More)
This study explores how people trust each other in Virtual Communities (VCs). The online presence is certainly different from the physical world.; the broad question in this research is whether trust is developed differently or not. The main sociological factors that influence trust in physical communities have been hypothesized for their contribution to(More)
Hybrid speciation represents a relatively rapid form of diversification. Early models of homoploid hybrid speciation suggested that reproductive isolation between the hybrid species and progenitors primarily resulted from karyotypic differences between the species. However, genic incompatibilities and ecological divergence may also be responsible for(More)
BACKGROUND Since 2003, it has been routine practice at Children's and Women's Health Centre of British Columbia to monitor serum levels of prolactin in pediatric patients with cystic fibrosis who are receiving domperidone. Although a pharmacologic relationship between domperidone and prolactin has been documented in the literature, there is no information(More)
Previous studies indicate that the presence of iron catalyzes DOM photo-oxidation. However, it is not clear that iron will affect DOM photobleaching in the same manner. The goal of this study is to examine the effect of iron on the rate of photobleaching in humic acid solutions, with the ultimate objective of comparing this effect with the effect iron has(More)
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