Sharif Burgette Mohr

Learn More
BACKGROUND Previous studies, such as the Women's Health Initiative, have shown that a low dose of vitamin D did not protect against colorectal cancer, yet a meta-analysis indicates that a higher dose may reduce its incidence. METHODS Five studies of serum 25(OH)D in association with colorectal cancer risk were identified using PubMed. The results of all(More)
Vitamin D and prevention of breast cancer: Pooled analysis Cedric F. Garland a,∗, Edward D. Gorham a, Sharif B. Mohr a, William B. Grant b, Edward L. Giovannucci c, Martin Lipkin d, Harold Newmark e,f, Michael F. Holick g, Frank C. Garland a a University of California, San Diego, Department of Family and Preventive Medicine, 9500 Gilman Drive, 0631C, La(More)
BACKGROUND Inadequate photosynthesis or oral intake of Vitamin D are associated with high incidence rates of colorectal cancer, but the dose-response relationship has not been adequately studied. METHODS Dose-response gradients from observational studies of Vitamin D intake and serum 25-hydroxyvitamin D were plotted as trend lines. The point on each(More)
PURPOSE Higher serum levels of the main circulating form of vitamin D, 25-hydroxyvitamin D (25(OH)D), are associated with substantially lower incidence rates of colon, breast, ovarian, renal, pancreatic, aggressive prostate and other cancers. METHODS Epidemiological findings combined with newly discovered mechanisms suggest a new model of cancer etiology(More)
This study is an analysis of the relationship between ultraviolet B (UVB) irradiance, the primary source of circulating vitamin D in humans, and age-standardised incidence rates of type 1 diabetes mellitus in children, according to region of the world. The association of UVB irradiance adjusted for cloud cover to incidence rates of type 1 diabetes in(More)
We examined the relationship between serum 25-hydroxyvitamin D (25[OH]D) and all-cause mortality. We searched biomedical databases for articles that assessed 2 or more categories of 25(OH)D from January 1, 1966, to January 15, 2013. We identified 32 studies and pooled the data. The hazard ratio for all-cause mortality comparing the lowest (0-9 nanograms per(More)
Low serum 25-hydroxyvitamin D [25(OH)D] concentration may increase risk of insulin-requiring diabetes. A nested case–control study was performed using serum collected during 2002–2008 from military service members. One thousand subjects subsequently developed insulin-requiring diabetes. A healthy control was individually matched to each case on blood-draw(More)
BACKGROUND Low serum levels of 25-hydroxyvitamin D [25(OH)D] have been associated with a high risk of breast cancer. Since publication of the most current meta-analysis of 25(OH)D and breast cancer risk, two new nested case-control studies have emerged. MATERIALS AND METHODS A PubMed search for all case-control studies on risk of breast cancer by 25(OH)D(More)
PURPOSE The purpose of this review is to summarize ecological studies of solar ultraviolet B (UVB), vitamin D and cancer since 2000. METHODS The journal literature is surveyed and summarized. RESULTS The ecological approach has been the primary tool used during the past two decades to extend the applicability of the UVB-vitamin D-cancer theory to(More)
BACKGROUND Sunscreens may allow overexposure to ultraviolet A (UVA) in fair-skinned persons and prevent symptoms of sunburn, but their benefits for the prevention of melanoma are uncertain. METHODS A PubMed search was performed that identified all known studies of the association of sunscreen use with melanoma risk during 1966-2007. A total of 18 studies(More)