Shaorong R Zhang

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PURPOSE To examine the adhesion of human trabecular meshwork cells with various extracellular matrix (ECM) proteins and to evaluate the roles and distribution of integrin receptors. METHODS Cultured human trabecular meshwork cells were added to 96-well plates either uncoated or coated with proteins including fibronectin, laminin, and vitronectin, as well(More)
PURPOSE The possible involvement of tissue transglutaminase (tTG) in apoptosis during photoreceptor degeneration was examined in retinal photic injury in rats and in retinal dystrophy of Royal College of Surgeons (RCS) rats. METHODS Retinal photic injury was induced in 48 male Lewis albino rats by exposure to green fluorescent light of 300 to 320(More)
Natural killer (NK) activity in the rat and human has been attributed to cells having the morphology of large granular lymphocytes (LGL). However, this association has been less clear in the mouse, largely because of difficulties in obtaining highly enriched populations of LGL from normal spleen and blood. We have previously observed that the administration(More)
Background: DNA vaccination is a convenient means of immunizing animals with recombinant parasite antigens. DNA delivery methods are believed to affect the qualitative nature of immune responses to DNA vaccines in ways that may affect their protective activity. However, relatively few studies have directly compared immune responses to plasmids encoding the(More)
A new class of MRI contrast agents has recently emerged that offers considerable potential for investigating biological events based on upon altering image contrast by a chemical exchange saturation transfer (CEST) mechanism. The first example of an exogenous CEST agent reported by Balaban and co-workers in 2000 [1] was a class of diamagnetic molecules that(More)
The clinical manife stations and CT scans of 14 cases of intracerebral tuberculomas were reviewed. 9 cases were associated with tuberculous meningitis. The images of the tuberculomas on CT scans appeared to be disc-like, ring-like or irregular in shape. The irregular mass consisted of multiple discs or rings coalescing to produce such irregular contours. On(More)
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