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Journals and Conferences
BACKGROUND Studies in rodent models of epilepsy suggest that multidrug efflux transporters at the blood-brain barrier, such as P-glycoprotein, might contribute to pharmacoresistance by reducing… (More)
BACKGROUND AND OBJECTIVES Cebranopadol is a novel first-in-class analgesic acting as a nociceptin/orphanin FQ peptide and opioid peptide receptor agonist with central analgesic activity. It is… (More)
For each simulation, PK profiles from 1000 subjects were simulated based on a titration scheme.