Shaolong Yang

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We have previously demonstrated that in a rat model of trauma-hemorrhage (T-H), glucosamine administration during resuscitation improved cardiac function, reduced circulating levels of inflammatory cytokines, and increased tissue levels of O-linked N-acetylglucosamine (O-GlcNAc) on proteins. The mechanism(s) by which glucosamine mediated its protective(More)
Survival after pancreatic cancer remains poor despite incremental advances in surgical and adjuvant therapy, and new strategies for treatment are needed. Oncolytic virotherapy is an attractive approach for cancer treatment. In this study, we have evaluated the effectiveness of the Lister vaccine strain of vaccinia virus armed with the endostatin-angiostatin(More)
Key Words: hemorrhagic shock ⅐ heart ⅐ estrogen receptor ⅐ mi-tochondria Despite numerous advances in intensive care medicine , ischemia/reperfusion injury, sepsis, and organ dysfunction leading to multiple organ failure remain the major cause of death in trauma patients as well as in patients following major surgery (1– 8). Previous studies have shown that(More)
Previous studies showed that females in the proestrus stage of the reproductive cycle maintain organ functions after trauma-hemorrhage. However, it remains unknown whether the female reproductive cycle is an important variable in the regulation of lung injury after trauma-hemorrhage and, if so, whether the effect is mediated via upregulation of heme(More)
In the present study, we investigated the effects of Se-enriched Agaricus blazei Murill (Se-AbM) on liver injury in mice induced by acute alcohol administration. Mice received ethanol (5 g/kg body weight (BW)) by gavage every 12 h for a total of 3 doses. Se-AbM was administrated before ethanol administration. Subsequent serum alanine aminotransferase (ALT)(More)
Since cardiac function is depressed in males but not in proestrus (PE) females following trauma-hemorrhage (T-H), we examined whether different estrus cycles influence cardiac function in female rats under those conditions. We hypothesized that females in the PE cycle only will have normal cardiac function following T-H and resuscitation. Sham operation or(More)
Although previous studies have shown that flutamide improves cardiovascular functions following trauma-hemorrhage (T-H), the mechanisms responsible for the salutary effect remain unknown. We hypothesized that flutamide mediates its beneficial effects via an estrogen-dependent pathway through upregulation of peroxisome proliferator-activated receptor(More)
Neurogenic neoplasms resulting from autonomic nerves are considerably rare. In this paper, we report a case of a 41-year-old woman with composite tumor of synchronous ganglioneuroma and schwannoma in the vagal inferior ganglion. Ultrasonography and computed tomography showed a well-defined mass, which extruded from the internal and external carotid(More)
The experiments were conducted to investigate the NO removal by wet scrubbing using NaClO2 seawater solution in a cyclic scrubbing mode. Results show that, when the concentration of NaClO2 in scrubbing solution is higher than 10 mM, a complete removal of NO can be achieved during the cyclic scrubbing process. The breakthrough time for seawater with 15 mM(More)
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