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BACKGROUND Cigarette smoking is the most established risk factor, and genetic variants and/or gene promoter methylations are also considered to play an essential role in development of lung cancer, but the pathogenesis of lung cancer is still unclear. METHODS We collected the data of 150 cases and 150 age-matched and sex-matched controls on a(More)
BACKGROUND Genetic factors were considered as one of the risk factors for lung cancer or other cancers. The aim of this work was to determine whether a genetic predisposition accounts for such familial aggregation of cancer among relatives of lung cancer probands. METHODS A case-control study was conducted in 800 case families identified by lung cancer(More)
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