Shao-nan Yan

Learn More
BACKGROUND It has been shown that telomerase activity and hepatitis B virus (HBV) replication are closely associated with cell cycle. This study aimed to further investigate the effects of cell cycle on telomerase activity and on HBV replication. METHODS Human hepatoma cells transfected with HBV DNA (HepG2 2.2.15 cell line) were treated respectively with(More)
BACKGROUND & OBJECTIVE Previous studies have shown that the expression of telomerase activity is closely correlated with the formation and development of tumor cells. Furthermore, the cell cycle is associated with hepatitis B virus (HBV) replication level and telomerase activity. For further study their relationship, this experiment was designed to(More)
OBJECTIVE To study the expression level and intracellular localization of APOBEC3G in peripheral blood mononuclear cells (PBMCs) and liver tissues of chronic HBV patients. METHODS The expression level and intracellular localization of APOBEC3G in PBMCs and liver tissues were detected using the western blot and confocal laser scanning microscope (CLSM). (More)
  • 1