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Alleviation of ovariectomy-induced osteoporosis in rats by Panax notoginseng saponins
TLDR
PNS treatment is able to enhance BMD, bone strength, and prevent the deterioration of trabecular microarchitecture without hyperplastic effect on uterus, and might be a potential alternative medicine for the prevention and treatment of postmenopausal osteoporosis. Expand
Simultaneous determination of nucleosides, myriocin, and carbohydrates in Cordyceps by HPLC coupled with diode array detection and evaporative light scattering detection.
TLDR
This developed HPLC coupled with diode array detection and evaporative light scattering detection method was successfully applied to quantify 12 components, eight nucleosides and nucleobases, three carbohydrates and myriocin, in natural and cultured Cordyceps, which provides another view for quality control of CordYceps sinensis. Expand
Qualitative and quantitative determination of nucleosides, bases and their analogues in natural and cultured Cordyceps by pressurized liquid extraction and high performance liquid
Abstract A simple and rapid pressurized liquid extraction (PLE) and high performance liquid chromatography–electrospray ionization tandem mass spectrometry (HPLC–ESI–MS/MS) method was developed forExpand
Chemical and pharmacological studies of Oplopanax horridus, a North American botanical
TLDR
The research status in the botany, phytochemistry, and pharmacology of OH is summarized, focusing more on the anticancer effects of OH and the involved mechanisms of action. Expand
Evaluation of antiproliferative activities and action mechanisms of extracts from two species of Ganoderma on tumor cell lines.
TLDR
This study showed that ethanol extracts of both G. lucidum and G. sinense have antitumoral proliferation effect through both apoptosis pathway and cell cycle arrest effect, and some other compounds such as sterols and/or nucleosides may contribute to their activity besides triterpenoids. Expand
Quality evaluation of Cordyceps through simultaneous determination of eleven nucleosides and bases by RP-HPLC.
TLDR
H hierarchical clustering analysis based on the typical peaks of adenosine, cordycepin, and inosine in HPLC profiles showed that natural and cultured Cordyceps were in different clusters, which could provide a means of discriminating between CordyCEps of different origins. Expand
Essential oil of Curcuma wenyujin induces apoptosis in human hepatoma cells.
TLDR
CWO exhibits an antiproliferative effect in HepG2 cells by inducing apoptosis, and results suggest a potential of CWO as a chemotherapeutic agent. Expand
A polysaccharide isolated from Cordyceps sinensis, a traditional Chinese medicine, protects PC12 cells against hydrogen peroxide-induced injury.
TLDR
This is the first report in identifying a polysaccharide from Cordyceps, which protects against the free radical-induced neuronal cell toxicity, and significantly attenuated the changes of glutathione peroxidase and superoxide dismutase activities in H(2)O(2)-treated cells in a dose-dependent manner. Expand
Inhibition of three selected beverage extracts on alpha-glucosidase and rapid identification of their active compounds using HPLC-DAD-MS/MS and biochemical detection.
TLDR
The study suggests that the developed LC-DAD-MS/MS-BCD system is a powerful tool for rapid screening and identification of alpha-glucosidase inhibitors in complex samples and that EGCG and ECG may be good candidates as alpha- glucosodase inhibitors. Expand
Chemical characteristics of three medicinal plants of the Panax genus determined by HPLC-ELSD.
TLDR
A high degree of similarity existed within individual clusters, but a low degree between the clusters, which could be used for quality control of the three CMs. Expand
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