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Dexamethasone suppresses DU145 cell proliferation and cell cycle through inhibition of the extracellular signal-regulated kinase 1/2 pathway and cyclin D1 expression.
TLDR
Observations suggest that dexamethasone has a potential clinical application in prostate cancer therapy, and the underlying mechanisms are through the inhibition of phosphorylation of ERK1/2 and cyclin D1 expression.
Identification of molecular characteristics induced by radiotherapy in rectal cancer based on microarray data.
TLDR
The biological processes or protein domains enriched by upregulated or downregulated DEGs may improve the understanding of molecular characteristics in response to radiotherapy.