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Dexamethasone suppresses DU145 cell proliferation and cell cycle through inhibition of the extracellular signal-regulated kinase 1/2 pathway and cyclin D1 expression.
- Qing Gao, Jia-ju Lu, Zi-dong Liu, H. Zhang, Shao-Mei Wang, He Xu
- Biology, MedicineAsian journal of andrology
- 1 July 2008
Observations suggest that dexamethasone has a potential clinical application in prostate cancer therapy, and the underlying mechanisms are through the inhibition of phosphorylation of ERK1/2 and cyclin D1 expression.
Identification of molecular characteristics induced by radiotherapy in rectal cancer based on microarray data.
- Chang Ge, Mengxia Wu, Guifang Chen, Guanying Yu, Dehui Ji, Shao-Mei Wang
- Biology, MedicineOncology letters
- 1 April 2017
The biological processes or protein domains enriched by upregulated or downregulated DEGs may improve the understanding of molecular characteristics in response to radiotherapy.