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OBJECTIVES Renal tract dilatation is a common finding in routine prenatal ultrasound. However, there is no consensus as to the criteria used for differentiating pathological from physiological dilatation. The aim of this study was to evaluate the natural history and postnatal outcome of fetal hydronephrosis in an unselected obstetric population. DESIGN(More)
OBJECTIVE To evaluate the prospective risk of stillbirth in multiple gestations. METHODS We conducted a retrospective analysis of birth notifications and infant mortality records relating to all multiple gestations to residents in a predefined health district. The incidence of live births and stillbirths was used to calculate the prospective risk of(More)
Advances in assisted reproductive technology and increases in the proportion of maternities in older women have both contributed to the steep increase in the incidence of twin pregnancies since the 1980s. Maternal and perinatal complications are higher in twins than in singleton pregnancies. A significant proportion of perinatal mortality and morbidity(More)
OBJECTIVE Assessing the role of fetal ductus venosus and nasal bones evaluation in first-trimester screening for Down syndrome. METHODS This was a prospective cohort study in a tertiary referral fetal medicine unit involving 628 consecutive fetuses undergoing chorionic villus sampling. The indication for chorionic villus sampling was an increased risk(More)
OBJECTIVE To assess the role of ductus venosus Doppler assessment in screening for fetal aneuploidy in pregnancies at 11-14 weeks of gestation. DESIGN Prospective observational study. SETTING A tertiary referral fetal medicine unit. POPULATION Two hundred fifty-six consecutive pregnancies between 11 and 14 weeks of gestation referred to our unit. (More)
OBJECTIVE To define the sonographic criteria which best determine the likelihood of successful expectant management of early pregnancy failure (EPF). METHODS Women with an ultrasound diagnosis of EPF at 7-14 weeks' gestation were offered the option of expectant management or surgical evacuation. RESULTS Five hundred and forty-five women had a diagnosis(More)
Development of the urogenital system in humans is a complex process; consequently, renal anomalies are among the most common congenital anomalies. The fetal urinary tract can be visualised ultrasonically from 11 weeks onwards, allowing recognition of megacystis at 11-14 weeks, which warrants comprehensive risk assessment of possible underlying chromosomal(More)
OBJECTIVE To establish the sensitivity of antenatal ultrasound for identifying the need for renal tract surgery in infancy and early childhood. METHODS A retrospective analysis of the surgical records in children under 5 years of age undergoing renal tract surgery in a regional pediatric urological surgery referral unit was carried out. All records(More)
OBJECTIVE In England an estimated 50,000 inductions of labour at or beyond 41 weeks' gestation are conducted each year. However, the published evidence on the effect of parity on stillbirth in prolonged pregnancy is limited, and has produced conflicting data. The aim of this study is to evaluate the influence of parity on fetal mortality in prolonged(More)
OBJECTIVE To evaluate the clinical application of simultaneous recordings of pulsed wave Doppler (PWD) signals in pulmonary artery and vein as alternative sampling site for assessment of arrhythmias in the fetus. DESIGN Prospective, cross-sectional study. SETTING Tertiary referral centre for fetal cardiology. PATIENTS AND METHODS From July 1999 to(More)