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Models of the geographic distributions of species have wide application in ecology. But the nonspatial, single-level, regression models that ecologists have often employed do not deal with problems of irregular sampling intensity or spatial dependence, and do not adequately quantify uncertainty. We show here how to build statistical models that can handle(More)
BACKGROUND Hepatocellular carcinoma (HCC) displays high resistance to conventional chemotherapy. Considering that microRNA-122 (miR-122) performs an essential function to promote chemosensitivity of HCC cells, an effective vehicle-mediated miR-122 delivery may represent a promising strategy for HCC chemotherapy. An increasing interest is focused on the use(More)
BACKGROUND Anti-tuberculosis drug induced liver injury (ATLI) is emerging as a significant threat to tuberculosis control in China, though limited data is available about the burden of ATLI at population level. This study aimed to estimate the incidence of ATLI, to better understand its clinical features, and to evaluate its impact on anti-tuberculosis (TB)(More)
AIMS Brachyury overexpression has been reported in various human malignant neoplasms, but its expression and function in hepatocellular carcinoma progression and metastasis remains unknown. The present study aimed to evaluate the critical role of Brachyury in HCC metastasis. METHODS The expression of Brachyury in human HCC (SMMC7721, HepG2, FHCC98, and(More)
Late diagnosis of hepatocarcinoma (HCC) is one of the most primary factors for the poor survival of patients. Thereby, identification of sensitive and specific biomarkers for HCC early diagnosis is of great importance in biological medicine to date. In the present study, serum metabolites of the HCC patients and healthy controls were investigated using the(More)
PURPOSE The goal of this study was to assess the effect of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on lipid profiles in patients with type 2 diabetes. METHODS The MEDLINE, Embase, Cochrane Library, and ClinicalTrials.gov databases were searched from inception through October 31, 2013. Randomized controlled trials with available data were(More)
AIMS Integrating evidence from all randomized controlled trials (RCTs) of glucagon-like peptide-1 receptor agonists (GLP-1s) to assess the safety of cardiovascular disease (CVD) and efficacy of glycemic control. METHODS Besides performing pairwise meta-analysis, network meta-analysis of all RCTs was used to combine direct and indirect estimates of the(More)
OBJECTIVES Little is known about work-related musculoskeletal disorders (WMSDs) among computer users mainland China. The aim of this study was to estimate the prevalence of WMSDs in office workers in Beijing, and to determine risk factors for WMSDs in the neck (WMSDs-N). METHODS In a cross-sectional study, a self-administered questionnaire was delivered(More)
This paper presents two different sensorless vector control methods for permanent magnet synchronous motor (PMSM) drive at very low speed range. One is high-frequency (HF) signal injection method, which utilizes the electromagnetic saliency of PMSM. The other one is low- frequency (LF) signal injection method, which is based only on the fundamental-wave(More)
A multi-antenna access point (AP) can communicate simultaneously with multiple clients, however, this multi-user MIMO (MU-MIMO) capability is underutilized in conventional 802.11 wireless LANs (WLANs). To address this problem, researchers have recently developed a CSMA/CA-based MAC protocol to support concurrent transmissions from different clients. In this(More)