Shanshan Mei

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OBJECTIVE To investigate the proportions of CD4+CD25high T cells and forkhead box p3 (FOXP3) expression in peripheral blood and decidua in patients with unexplained recurrent spontaneous abortion (URSA). DESIGN Prospective clinical study. SETTING University hospital. PATIENT(S) 125 URSA patients, 35 normal early pregnant women, and 28 normal(More)
Patients with non-lesional or bilateral temporal-lobe epilepsy (TLE) are often excluded from surgical treatment. This study investigated focus lateralization in TLE to understand identification of the affected hemisphere with regard to non-lesional or bilateral affection and postsurgical outcome. A total of 24 TLE patients underwent presurgical evaluation(More)
Although epilepsy surgery is an effective treatment for patients with drug-resistant epilepsy, surgical outcomes vary across patient groups and studies. Identification of reliable prognostic factors for surgical outcome is important for outcome research. In this study, recent systematic reviews and meta-analyses on prediction of seizure outcome have been(More)
Intracranial EEG (icEEG) monitoring is critical in epilepsy surgical planning, but it has limitations. The advances of neuroimaging have made it possible to reveal epileptic abnormalities that could not be identified previously and improve the localization of the seizure focus and the vital cortex. A frequently asked question in the field is whether(More)
AIMS To investigate the expression and clinical significance of flotillin-2 (FLOT2) in cervical cancer (CC). METHODS We examined FLOT2 mRNA levels in 10 pairs of cervical cancer and adjacent normal tissues. Immunohistochemistry was performed to analyze FLOT2 protein expression in 115 archived cervical cancer samples. The association between FLOT2 levels,(More)
Hemispherectomy is effective for young patients suffered from unilateral cortical disease and severe drug-resistant epilepsy, but a major concern for hemispherectomy is the remaining brain functions and function recovery in patients after such surgery. In this study, seven patients were evaluated with clinical and imaging assessment pre- and post-surgery.(More)
Simultaneous EEG-fMRI is a non-invasive investigation technique developed to localize the generators of interictal epileptiform discharges (IED) in patients with epilepsy. Although the value of EEG-fMRI in epilepsy presurgical evaluation is being assessed clinically, its utility is still controversial. In this review, we considered EEG-fMRI applications in(More)
Epilepsy surgery has improved over the last decade, but non-seizure-free outcome remains at 10%-40% in temporal lobe epilepsy (TLE) and 40%-60% in extratemporal lobe epilepsy (ETLE). This paper reports a complex multifocal case. With a normal magnetic resonance imaging (MRI) result and nonlocalizing electroencephalography (EEG) findings (bilateral TLE and(More)
OBJECTIVE To carry out a retrospective study of the clinical features of patients with intrauterine hematoma in the second and third trimesters, and discuss the risk factors for poor pregnancy outcomes. METHODS A total of 398 patients who underwent routine examination in our hospital from January 2011 to December 2015 were classified into normal pregnancy(More)
Pelvic organ prolapse (POP) is a prevalent and disabling condition. The pathophysiology of prolapse is multifactorial, and no single mechanism adequately explains all aspects of its development. The pathophysiology of POP is complex and incompletely understood. Smooth muscle (SM), an integral part of the vaginal wall and endopelvic structures that support(More)