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  • Dominique B. Hoelzinger, Shannon E. Smith, Noweeda Mirza, Ana Lucia Dominguez, Soraya Zorro Manrique, Joseph Lustgarten
  • Medicine, Biology
  • The Journal of Immunology
  • 2010 (First Publication: 15 June 2010)
  • Intratumoral accumulation of T regulatory cells (Tregs) creates an immunosuppressive environment that reduces the efficacy of antitumor immunotherapy. The immunosuppressive milieu within tumors isExpand
  • Shannon E. Smith, Dominique B. Hoelzinger, Ana Lucia Dominguez, Jacques van Snick, Joseph Lustgarten
  • Biology, Medicine
  • Cancer Immunology, Immunotherapy
  • 2011 (First Publication: 26 July 2011)
  • Previous studies from our laboratory indicate that intratumoral (i.t.) injections of CpG-ODN are the most effective adjuvant strategy to induce an antitumor immune response in tolerant BALB-neuT miceExpand
  • Shannon E. Smith, Daniel A. Holterman, +6 authors David Spetzler
  • Biology
  • 2012 (First Publication: 15 April 2012)
  • Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL MicroRNAs (miRs) are small non-coding RNAs that are 20 to 25 nucleotides in length and regulate expression of entireExpand