Shannon C. Lehr

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downregulates vascular endothelial Flk-1 expression in human melanoma xenograft model. TNF with melphalan has significant antitumor activity in regional perfusion of the limbs and liver in human malignan-cies. TNF is believed to target tumor vasculature, but the precise molecular mechanism is unknown. The present study demonstrates that TNF downregulates(More)
BACKGROUND The most frequent wound complication following repair of large incisional hernias is seroma formation, especially when the use of a mesh onlay requires extensive subcutaneous undermining. Treatment options for postoperative seromas include observation for spontaneous resolution, percutaneous aspiration, closed suction drainage, abdominal binders,(More)
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