Shang-bang Gao

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AbstractAim:Na+-activated K+ (KNa) channels set and stabilize resting membrane potential in rat small dorsal root ganglion (DRG) neurons. However, whether KNa channels play the same role in other size DRG neurons is still elusive. The aim of this study is to identify the existence and potential physiological functions of KNa channels in medium diameter(More)
Auxiliary beta-subunits associated with pore-forming Slo1 alpha-subunits play an essential role in regulating functional properties of large-conductance, voltage- and Ca(2+)-activated K(+) channels commonly termed BK channels. Even though both noninactivating and inactivating BK channels are thought to be regulated by beta-subunits (beta1, beta2, beta3, or(More)
Calcium-activated chloride channels (CaCCs) are crucial regulators of vascular tone by promoting a depolarizing influence on the resting membrane potential of vascular smooth muscle cells. However, the lack of a special blocker of CaCCs has limited the investigation of its functions for long time. Here, we report that CB is a novel potential blocker of(More)
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