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SUMMARY The alignment of multiple homologous biopolymer sequences is crucial in research on protein modeling and engineering, molecular evolution, and prediction both as to gene function and gene product's structure. In this article, we provide a coherent view of the two recent models used for multiple sequence alignment | the hidden Markov model (HMM) and(More)
Identifying conserved gene clusters is an important step toward understanding the evolution of genomes and predicting the functions of genes. A famous model to capture the essential biological features of a conserved gene cluster is called the gene-team model. The problem of finding the gene teams of two general sequences is the focus of this paper. For(More)
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