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Anecdotal evidence suggests that some dogs may be able to sense the onset of seizures and other medical conditions in humans, although this has never been explored scientifically. There is, however, evidence that dogs can be specially trained to recognize specific changes preceding a seizure and give an overt signal enabling the dog to warn his/her owner.(More)
Eight patients rechallenged with lamotrigine after initial exposure which resulted in a skin rash are reported. On reintroduction of the lamotrigine, six of the patients had no recurrence of the rash. Of the other two patients, one had the occurrence of a mild fluctuating and qualitatively different skin rash on rechallenge. The other patient had developed(More)
We report a prospective series of 18 patients with a diagnosis of non-epileptic seizures (NES, pseudoseizures) identified in one unit. Sixteen patients agreed to complete a therapeutic programme. At the end of treatment eight were seizure free, three had only occasional NES and five were unchanged. At 1-year follow-up the situation remained similar(More)
The inhibition of seizure activity by behavioural methods is becoming more popular. Lockhart's monkey model of focal epilepsy suggests a theoretical approach to behavioural seizure inhibition. Behaviour, by changing the pattern of excitation and inhibition surrounding a focus, is thus able to inhibit seizure activity. This article describes single case(More)
EEG with co-registered electrocardiography was recorded during at least two interictal epileptiform EEG discharges in each of 11 patients who later suffered from sudden unexpected death in epilepsy (SUDEP), and from another 11 age and sex matched patients, also with uncontrolled tonic-clonic seizures, drawn from the same centre who were still alive at the(More)
The precipitation of seizures by external stimulation (evoked seizures) is well known. Less well known is the precipitation of seizures by a change in the patient's thinking or feelings. This artick uses Lockhart's monkey model of focal epilepsy to propose that there is a close relationship between seizures and ongoing brain activity. Thus, seizures(More)
Epilepsy is a common condition in people with learning difficulties. The assessment of seizure disorders in this group requires special consideration of psychological and social, as well as medical, aspects. We consider an integrated approach assessing epilepsy and learning difficulties in parallel. Such meticulous assessment can lead to improved quality of(More)