Shan Guo

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INTRODUCTION Coexistence of pulmonary embolism and systemic arterial embolism suggest the diagnosis of paradoxical embolism which suggests the presence of intracardiac defects such as patent foramen ovale (PFO). CASE PRESENTATION A 42 year old man was found to have a paradoxical embolism in the systemic arterial circulation, in the setting of pulmonary(More)
OBJECTIVES We aimed to determine the seroprevalence of Crimean-Congo hemorrhagic fever virus (CCHFV) infection in Yunnan Province, China. MATERIALS AND METHODS One thousand six hundred and fifty-seven human serum samples and 1280 ticks (Hyalomma asiaticum) were collected from five counties (Menglian, Menghai, Lancang, Mengla, and Ximeng). Serum samples(More)
BACKGROUND Qinghai Lake in central China has been at the center of debate on whether wild birds play a role in circulation of highly pathogenic avian influenza virus H5N1. In 2005, an unprecedented epizootic at Qinghai Lake killed more than 6000 migratory birds including over 3000 bar-headed geese (Anser indicus). H5N1 subsequently spread to Europe and(More)
Sinonasal undifferentiated carcinoma (SNUC) is a rare and highly malignant tumor that occurs in the nasal cavity and/or paranasal sinuses. Prognosis is poor despite multimodality treatment. Currently, there is no optimal standard of treatment, partially due to a lack of research defining the biology of such tumors. This report discusses two SNUC cases where(More)
Bone is one of the most frequent targets of small cell lung cancer (SCLC) metastasis, but the molecular mechanism remains unclear. β3-integrin plays an important role in invasion of various kinds of tumors. Yet, its role in bone-metastasis of SCLC is still unknown. In this study, we first examined the expression of β3-integrin in SBC-5 and SBC-3 cells by(More)
The objective of this study is to develop techniques for assessing and analysing land desertification in Yulin of Northwest China, as a typical monitoring region through the use of remotely sensed data and geographic information systems (GIS). The methodology included the use of Landsat TM data from 1987, 1996 and 2006, supplemented by aerial photos in(More)
BACKGROUND The highly pathogenic H5N1 avian influenza emerged in the year 1996 in Asia, and has spread to Europe and Africa recently. At present, effective monitoring and data analysis of H5N1 are not sufficient in Chinese mainland. METHODOLOGY/PRINCIPAL FINDINGS During the period from April of 2004 to August of 2007, we collected 14,472 wild bird samples(More)
The highly pathogenic avian influenza H5N1 virus still cause devastating effects to humans, agricultural poultry flocks, and wild birds. Wild birds are also detected to carry H5N1 over long distances and are able to introduce it into new areas during migration. In this article, our objective is to provide lists of bird species potentially involved in the(More)
Gastric carcinoma is the most malignant tumor. Due to lacking of efficient means to diagnose the cancer at the early stage, it is necessary to develop effective molecular probes for early diagnosis and treatment. We have selected aptamers with high specificity and affinity against SGC7901 cells by cell-SELEX (Systematic Evolution of Ligands by Exponential(More)
Ceramides are known to be a key component of the stratum corneum, the outermost protective layer of the skin that controls barrier function. In this work, molecular dynamics simulations are used to examine the behavior of ceramide bilayers, focusing on non-hydroxy sphingosine (NS) and non-hydroxy phytosphingosine (NP) ceramides. Here, we propose a modified(More)