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Atorvastatin calcium is a lipid-lowering agent. It has approximately 15% of bioavailability, remaining amount of drug showed adverse effect which is undesirable for patients. The objective of the study was to enhance the solubility and a dissolution profile of the atorvastatin (AT) calcium. Solid dispersion (SD) is a technique which enhances the solubility(More)
INTRODUCTION Solubility and dissolution of a poor water-soluble drug are the two major barriers for formulation scientists in development of drug delivery. Many of the potent drugs do not show the therapeutic effects due to solubility issues but may show toxicity issues when used in high doses. Solid dispersion (SD) technology is an excellent tool for(More)
Internet today has become a victim of its own success. As the internet is reaching a global community, the World Wide Web is becoming a global-scale data dissemination system. There has been an increase in user latency, bandwidth utilization and server loads because of the increased number of World Wide Web users. Web caching is a technology for overcoming(More)
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