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Type II alveolar epithelial cells (AEC) can produce various antimicrobial and proinflammatory effector molecules. This, together with their abundance and strategic location, suggests a role in host defense against pulmonary pathogens. We report that murine type II AEC, like their human counterparts, express class II major histocompatibility complex (MHC).(More)
The power graph of a group is the graph whose vertex set is the group, two elements being adjacent if one is a power of the other. We observe that non-isomorphic finite groups may have isomorphic power graphs, but that finite abelian groups with isomorphic power graphs must be isomorphic. We conjecture that two finite groups with isomorphic power graphs(More)
Host immunity to Mycobacterium tuberculosis is mediated by T cells that recognize and activate infected macrophages to control intracellular bacterial replication. The early appearance of T cells in the lungs of infected mice correlates with greater resistance to infection. However, it is unknown whether the trafficking of T cells to the lung following(More)
Almost any microorganism has the potential to infect the human central nervous system. Neurosurgical intervention may be required for tissue assay, to establish a microbiologic diagnosis, for decompression of space-occupying lesions with significant mass effects, or for definitive treatments such as cerebrospinal fluid diversion. This article surveys the(More)
Notch3 signaling is fundamental for arterial specification of systemic vascular smooth muscle cells (VSMCs). However, the developmental role and signaling properties of the Notch3 receptor in the mouse pulmonary artery remain unknown. Here, we demonstrate that Notch3 is expressed selectively in pulmonary artery VSMCs, is activated from late fetal to early(More)
Effect of M. tuberculosis infection was studied on the expression of intercellular adhesion molocule-1 (ICAM-1) and Mac-1 markers on murine peritoneal macrophages. Intraperitoneal administration of M. tuberculosis resulted in a marked increase in the proportion of Mac-1(+) cells whereas the proportion of ICAM-1(+) cells declined sharply 4 h post infection.(More)