Sham Sokka

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The cardiovascular response to changes in posture has been the focus of numerous investigations in the past. Yet despite considerable, targeted experimental effort, the mechanisms underlying orthostatic intolerance (OI) following spaceflight remain elusive. The number of hypotheses still under consideration and the lack of a single unifying theory of the(More)
Objective Cardiovascular intervention guidance requires knowledge of heart function relative to its blood supply or venous drainage. Functional and vascular anatomic data are usually generated on different imaging systems, so fusion of the data is necessary to simultaneously visualize the results for intervention planning and guidance. The objective of this(More)
Clinical use of high-intensity focused ultrasound (HIFU) under ultrasound or MR guidance as a non-invasive method for treating tumors is rapidly increasing. Tens of thousands of patients have been treated for uterine fibroid, benign prostate hyperplasia, bone metastases, or prostate cancer. Despite the methods' clinical potential, the liver is a(More)
Temperature monitoring is most important during the application of thermal treatment, such as in the case of Focused Ultrasound Surgery (FUS). Currently, Magnetic Resonance Imaging (MRI) is the predominant method for temperature mapping of FUS. However, its high cost, low temporal resolution and limited availability and applicability often result in its(More)
The cytoskeleton is a dense network of partially crosslinked filamentous actin that provides structure to cells. Modeling this complicated network requires understanding how its individual elements interact. Filamin 1 (known previously as ABP or ABP-280) is a large 2x280.5 kDa dimeric actin crosslinking protein found in eukaryotic cells that promotes actin(More)
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