Shakirahmed Kolia

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PURPOSE To address the progression, metastasis, and clinical heterogeneity of renal cell cancer (RCC). EXPERIMENTAL DESIGN Transcriptional profiling with oligonucleotide microarrays (22,283 genes) was done on 49 RCC tumors, 20 non-RCC renal tumors, and 23 normal kidney samples. Samples were clustered based on gene expression profiles and specific gene(More)
PURPOSE We investigated whether tumor tissue obtained at diagnosis expresses a specific gene profile that is predictive of findings at second-look surgery in patients with epithelial ovarian cancer (EOC). PATIENTS AND METHODS Tumor tissue obtained at the time of diagnosis was profiled with oligonucleotide microarrays. Class prediction analysis was(More)
In the post-genomic era, the availability of complete genome sequences has given rise to high throughput systems such as gene chips and protein arrays. These techniques revolutionize our understanding of biology by simultaneously probing thousands of biological entities at any given time. Unsupervised classification and clustering have emerged as important(More)
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