Shaista Rashid

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BACKGROUND The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), result from the combined effects of susceptibility genes and environmental factors. Previous studies have shown that polymorphisms in the Toll-like receptor (TLR), the apoptosis, the IL-23/IL-17 and the interferon gamma (IFNG) pathways are associated with(More)
An otherwise healthy 49-year-old male was admitted due to ascites and obstipation. He had no history of atopy. He went through an extensive diagnostic workup including laparascopy and bone marrow biopsy. All the tests came out normal except for a large number of eosinophils in the blood and the ascites. The diagnosis of idiopatic eosinophilic ascites was(More)
BACKGROUND The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), result from the combined effects of susceptibility genes and environmental factors. Polymorphisms in genes regulating inflammation may explain part of the genetic heritage. METHODS Using a candidate gene approach, 39 mainly functional single nucleotide(More)
INTRODUCTION The objective of this study was to evaluate the outcome of anti-tumour necrosis factor-α (anti-TNF) treatment in a large cohort of patients with inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC) in clinical practice and to establish a cohort for future studies of genetic markers associated with(More)
In all walks of life individuals are involved in a cumulative and incremental process of knowledge acquisition. This involves the accessing, processing and understanding of information which can be gained through many different forms. These include, deliberate means by picking up a book or passive by listening to someone. The content of knowledge is(More)
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