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- Ravindra Sunil Dhumal, Shailesh V. Biradar, Shigeo Yamamura, Anant R. Paradkar, Peter York
- European journal of pharmaceutics and…
- 2008
The aim of the present work was to prepare amorphous discreet nanoparticles by sonoprecipitation method for enhancing oral bioavailability of cefuroxime axetil (CA), a poorly water-soluble drug. CA… (More)
- Ravindra Sunil Dhumal, Shailesh V. Biradar, Suyog Aher, Anant R. Paradkar
- The Journal of pharmacy and pharmacology
- 2009
OBJECTIVES
Cefuroxime axetil (CA), a poorly soluble, broad spectrum cephalosporin ester prodrug, is hydrolysed by intestinal esterase prior to absorption, leading to poor and variable… (More)
- Ravindra Sunil Dhumal, Shailesh V. Biradar, Anant R. Paradkar, Peter York
- Pharmaceutical Research
- 2008
PurposeTo engineer lactose crystals of desired size, shape, surface and particle size distribution (PSD) as a carrier for dry powder inhalers (DPI) by ultrasound assisted in-situ… (More)
- Pradeep R. Patil, Shailesh V. Biradar, Anant R. Paradkar
- AAPS PharmSciTech
- 2009
The purpose of the present study was to formulate a self-nanoemulsifying system (SNES) containing model lipophilic drug, felodipine (FLD), to improve its solubility. The SNES was formulated using… (More)
- Rahul Tripathi, Shailesh V. Biradar, Brahmeshwar Mishra, Anant R. Paradkar
- AAPS PharmSciTech
- 2010
A large number of pharmaceuticals exhibit polymorphism; 23% steroids, 60% sulfonamides, and 70% of barbiturates have shown this property. In this study, we have investigated and compared a new… (More)
Abstract Roxithromycin (ROX), a class IV drug has 50% absolute oral bioavailability due to poor aqueous solubility. The present study deals with exploring the effect of homogenization, homogenization… (More)
Objectives Piperine is one of the most promising bioenhancers to date. Methods used for its extraction suffer from drawbacks such as use of organic solvents, poor extraction efficiency, tedious and… (More)
- Manish H. Shah, Shailesh V. Biradar, Anant R. Paradkar
- International journal of pharmaceutics
- 2006
Glyceryl monooleate (GMO) is a polar amphiphilic lipid, which forms different sequential lyotropic liquid crystals upon hydration. GMO has been utilized for various delivery systems and routes of… (More)
- Shailesh V. Biradar, Ravindra Sunil Dhumal, Anant R. Paradkar
- Journal of pharmacy & pharmaceutical sciences : a…
- 2009
PURPOSE
Aim of this study is to investigate the mechanism of self-emulsification through rheological analysis of intermediate liquid crystalline (LC) phase formed during self-emulsification process.… (More)
- Shailesh V. Biradar, Ravindra Sunil Dhumal, Ananat R Paradkar
- Journal of pharmacy & pharmaceutical sciences : a…
- 2009
PURPOSE
The aim of study is to investigate role of co-surfactant in self-emulsification through rheological analysis of intermediate liquid crystalline (LC) phase formed during self-emulsification.… (More)